NextDose Bayesian forecasting dose calculator

A free web-based dose calculator using concentration guided dosing with Bayesian forecasting and the target concentration intervention approach
for busulfan, methotrexate, tacrolimus, warfarin, linezolid, voriconazole, gentamicin, tobramycin, amikacin, vancomycin, caffeine, mycophenolate, hydroxychloroquine, dabigatran, posaconazole, gancyclovir/valgancyclovir, clozapine and enoxaparin.

29-Jun-2026: NextDose Version Change to 2.6.01
-Bug fix: A problem adding new Doses has been fixed.

29-Jun-2026: NextDose Version Change to 2.6.00
-NextDose Privacy Issue: A privacy issue was detected on 25-Jun-2026. In order to investigate the issue it was necessary to close down user access to NextDose. The cause of the issue was identified and fixed. No patient data was compromised.

04-May-2026: Apologies for Major NextDose Results Failure.
-A premature fix for the bug finally fixed 5-May-2026 introduced a major bug that caused all attempts to calculate NextDose Results to fail with an FSTREAM error. Thanks to all NextDose users who reported the problem which helped me find and fix this bug. My apologies to all NextDose users for causing this problem by not adequately testing the changes I had made on 4-May-2026. I have tested the fix. Please let me know if you notice any other unusual NextDose behaviour. Nick Holford.

05-May-2026: NextDose Version Change to 2.5.02
- Bug fix: Uncommon combination of covariates used to calculate fat free mass caused a numerical error in some special cases. This bug has now been fixed.

- Feedback, and the reporting of any issues encountered, is always appreciated.

NextDose Updates

Anyone may sign up for single user access. Access to share patient data within a secure group can be applied for here.

Note that patient data stored on dev.nextdose.org is not transferable to www.nextdose.org. The dev.nextdose.org web is under active development and may change without notice as features are tested and bugs fixed.